Development and validation of the European League Against Rheumatism response criteria for rheumatoid arthritis: comparison with the preliminary American …

AM Van Gestel, MLL Prevoo… - … : Official Journal of …, 1996 - Wiley Online Library
AM Van Gestel, MLL Prevoo, MA Van't Hof, MH Van Rijswijk, LBA Van de Putte, P Van Riel
Arthritis & Rheumatism: Official Journal of the American College …, 1996Wiley Online Library
Abstract Objective. To validate the European League Against Rheumatism (EULAR), the
American College of Rheumatology (ACR), and the World Health Organization
(WHO)/International League Against Rheumatism (ILAR) response criteria for rheumatoid
arthritis (RA). Methods. EULAR response criteria were developed combining change from
baseline and level of disease activity attained during followup. In a trial comparing
hydroxychloroquine and sulfasalazine, we studied construct (radiographic progression) …
Abstract
Objective. To validate the European League Against Rheumatism (EULAR), the American College of Rheumatology (ACR), and the World Health Organization (WHO)/International League Against Rheumatism (ILAR) response criteria for rheumatoid arthritis (RA).
Methods. EULAR response criteria were developed combining change from baseline and level of disease activity attained during followup. In a trial comparing hydroxychloroquine and sulfasalazine, we studied construct (radiographic progression), criterion (functional capacity), and discriminant validity.
Results. EULAR response criteria had good construct, criterion, and discriminant validity. ACR and WHO/ILAR criteria showed only good criterion validity.
Conclusion. EULAR response criteria showed better construct and discriminant validity than did the ACR and the WHO/ILAR response criteria for RA.
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