Adhesion molecule expression and regulation on cells of the central nervous system
SJ Lee, EN Benveniste - Journal of neuroimmunology, 1999 - Elsevier
Cellular adhesion molecules were initially defined as cell surface structures mediating cell–
cell and cell–extracellular matrix (ECM) interactions. Adhesion molecules involved in
immune responses have been classified into three families according to their structure:
selectins, immunoglobulin (Ig) superfamily, and integrins. It has been well documented that
adhesion molecules of these family members (E-selectin, ICAM-1, and VCAM-1) are
expressed on brain microvessel endothelial cells in active lesions of multiple sclerosis (MS) …
cell and cell–extracellular matrix (ECM) interactions. Adhesion molecules involved in
immune responses have been classified into three families according to their structure:
selectins, immunoglobulin (Ig) superfamily, and integrins. It has been well documented that
adhesion molecules of these family members (E-selectin, ICAM-1, and VCAM-1) are
expressed on brain microvessel endothelial cells in active lesions of multiple sclerosis (MS) …