Transmission electron microscopic study of a subretinal choroidal neovascular membrane due to age-related macular degeneration
KM Gehrs, WJ Heriot, E de Juan - Archives of Ophthalmology, 1992 - jamanetwork.com
• From a patient with age-related macular degeneration we studied ultrastructurally a
disciform scar that was removed from an eye with a vitreous hemorrhage. In cross section,
the scar was divided by a retinal pigment epithelial (RPE) cell layer. The choroidal side
consisted of fibrovascular tissue with active neovascular buds and inflammatory cells,
including macrophages attached to the RPE basement membrane. Apart from the RPE, no
components of Bruch's membrane could be identified. The retinal side contained organizing …
disciform scar that was removed from an eye with a vitreous hemorrhage. In cross section,
the scar was divided by a retinal pigment epithelial (RPE) cell layer. The choroidal side
consisted of fibrovascular tissue with active neovascular buds and inflammatory cells,
including macrophages attached to the RPE basement membrane. Apart from the RPE, no
components of Bruch's membrane could be identified. The retinal side contained organizing …
