[HTML][HTML] A functional variant in the thrombospondin‐1 gene and the risk of small for gestational age infants

PH Andraweera, GA Dekker, SD Thompson… - Journal of Thrombosis …, 2011 - Elsevier
Summary Introduction: Thrombospondin‐1 (TSP‐1) is a prothrombotic and anti‐angiogenic
glycoprotein expressed in the placenta. A functional single nucleotide polymorphism in the
TSP‐1 gene (TSP‐1 A2210G) is a risk factor for familial premature myocardial infarction.
Small for gestational age (SGA) infants are at increased risk of coronary artery disease in
adult life and common genetic factors may underlie both conditions. We investigated the
association of TSP‐1 A2210G in SGA infants and their parents. Method: The 3234 …