Cellular and molecular biology of optineurin
H Ying, BYJT Yue - International review of cell and molecular biology, 2012 - Elsevier
Optineurin is a gene linked to glaucoma, amyotrophic lateral sclerosis, other
neurodegenerative diseases, and Paget's disease of bone. This review describes the
characteristics of optineurin and summarizes the cellular and molecular biology
investigations conducted so far on optineurin. Data from a number of laboratories indicate
that optineurin is a cytosolic protein containing 577 amino acid residues. Interacting with
proteins such as myosin VI, Rab8, huntingtin, transferrin receptor, and TANK-binding kinase …
neurodegenerative diseases, and Paget's disease of bone. This review describes the
characteristics of optineurin and summarizes the cellular and molecular biology
investigations conducted so far on optineurin. Data from a number of laboratories indicate
that optineurin is a cytosolic protein containing 577 amino acid residues. Interacting with
proteins such as myosin VI, Rab8, huntingtin, transferrin receptor, and TANK-binding kinase …
