Lesion of the subthalamic nucleus for the alleviation of 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine (MPTP)‐induced parkinsonism in the primate
TZ Aziz, D Peggs, MA Sambrook… - … : official journal of the …, 1991 - Wiley Online Library
TZ Aziz, D Peggs, MA Sambrook, AR Crossman
Movement disorders: official journal of the Movement Disorder Society, 1991•Wiley Online LibraryCentral to the neural mechanism of MPTP‐induced parkinsonism is overactivity of the
subthalamic nucleus. Lesion of the subthalamic nucleus has therefore been performed in
two primates with this condition and found to produce a remarkable amelioration of the
disorder.
subthalamic nucleus. Lesion of the subthalamic nucleus has therefore been performed in
two primates with this condition and found to produce a remarkable amelioration of the
disorder.
Abstract
Central to the neural mechanism of MPTP‐induced parkinsonism is overactivity of the subthalamic nucleus. Lesion of the subthalamic nucleus has therefore been performed in two primates with this condition and found to produce a remarkable amelioration of the disorder.
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