Pathogenic Mechanisms Our philosophic models of infection are based on concepts of
microbial monoetiology. Pasteur demonstrated that certain micro-organisms were
responsible for specific syndromes. This concept was formalized into its present liturgical
style by Robert Koch in his famous" Postulates." To complete the trilogy, Erhlich created a"
magic bullet," the drug designed for a specific infection. In its final form, this principle reads:
one microbe-one disease-one drug. The concept of monoetiology applies to infections such …