Analysis with the Combur-Test--special aspects in forensic trace examination

PJ Laberke, R Hausmann, N Wiprächtiger… - Archiv fur …, 2012 - europepmc.org
PJ Laberke, R Hausmann, N Wiprächtiger, T Briellmann, B Balitzki
Archiv fur Kriminologie, 2012europepmc.org
The Combur Test is a ready-made and easy-to-use pretest for blood. It is based on the
oxidation of tetramethylbenzidine (TMB), which is catalysed by haemoglobin and its
derivatives. Despite its high sensitivity, there are many known substances which are
responsible for false positive and false negative test results. On the basis of experiments of
our own, case reports and the pertinent literature special aspects of the application of the
Combur Test in the forensic routine case work are discussed.
The Combur Test is a ready-made and easy-to-use pretest for blood. It is based on the oxidation of tetramethylbenzidine (TMB), which is catalysed by haemoglobin and its derivatives. Despite its high sensitivity, there are many known substances which are responsible for false positive and false negative test results. On the basis of experiments of our own, case reports and the pertinent literature special aspects of the application of the Combur Test in the forensic routine case work are discussed.
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