[HTML][HTML] Integrating mRNA processing with transcription
NJ Proudfoot, A Furger, MJ Dye - Cell, 2002 - cell.com
NJ Proudfoot, A Furger, MJ Dye
Cell, 2002•cell.comThe messenger RNA processing reactions of capping, splicing, and polyadenylation occur
cotranscriptionally. They not only influence one another's efficiency and specificity, but are
also coordinated by transcription. The phosphorylated CTD of RNA polymerase II provides
key molecular contacts with these mRNA processing reactions throughout transcriptional
elongation and termination.
cotranscriptionally. They not only influence one another's efficiency and specificity, but are
also coordinated by transcription. The phosphorylated CTD of RNA polymerase II provides
key molecular contacts with these mRNA processing reactions throughout transcriptional
elongation and termination.
Abstract
The messenger RNA processing reactions of capping, splicing, and polyadenylation occur cotranscriptionally. They not only influence one another's efficiency and specificity, but are also coordinated by transcription. The phosphorylated CTD of RNA polymerase II provides key molecular contacts with these mRNA processing reactions throughout transcriptional elongation and termination.
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